Peter Vadas MD, PhD

Allergist and Clinical Immunologist

Anaphylaxis Related Activities

  • Lead Canadian investigator, A Phase II, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Oral Food Challenge Trial of Xolair (Omalizumab) in Peanut Allergy
  • Investigator, Epicutaneous Immunotherapy (EPIT) for Peanut Allergy: A Randomized, Double-Blind, Placebo-Controlled Phase IIb/III Safety and Efficacy Study in Adult and Pediatric Subjects
  • Director of Allergy and Clinical Immunology at St. Michael's Hospital
  • Medical Director of the Regional Anaphylaxis Clinic
  • Past President of the Anaphylaxis Foundation of Canada
  • Past Chair of the Anaphylaxis Committee of the American Academy of Allergy, Asthma and Immunology
  • Past Head, Section of Anaphylaxis and Adverse Reactions of the Canadian Society of Allergy and Clinical Immunology
  • Past head of the Section of Allergy and Clinical Immunology of the Ontario Medical Association
  • Former member, Board of Examiners for Allergy and Clinical Immunology, Royal College of Physicians and Surgeons of Canada
  • Member, Scientific Advisory Committee, National Peanut Board
  • Member, Medical Advisory Board, Anaphylaxis Canada
  • Member, Medical Advisory Board, Allergy Asthma Information Association

Selected Publications in Food Allergies and Anaphylaxis

Peer-Reviewed Publications

§  Vadas P, Gold M, Perelman B, Liss GM, Lack G, Blyth T, Simons FE, Simons KJ, Cass D, Yeung J.  Platelet-activating factor, PAF acetylhydrolase, and severe anaphylaxis.  New England Journal of Medicine 2008 Jan 3;358(1):28-35.

§  Arias K, Baig M, Colangelo M, Chu D, Walker T, Goncharova S, Coyle A, Vadas P, Waserman S, Jordana M.  Concurrent blockade of platelet-activating factor and histamine prevents life-threatening peanut-induced anaphylactic reactions.  J Allergy Clin Immunol. 2009 Aug;124(2):307-14

§  Vadas P, Perelman B.  Presence of undeclared peanut protein in chocolate bars imported from Europe.  J Food Prot. 2003 Oct; 66(10):1932-4.

§  Vadas P, Perelman B.  Activated charcoal forms non-IgE binding complexes with peanut proteins.  J Allergy Clin Immunol. 2003 Jul;112(1):175-9.

§  Vadas P, Wai Y, Burks W, Perelman B.  Detection of peanut allergens in breast milk of lactating women.  JAMA. 2001 Apr 4;285(13):1746-8.

§  Taylor SL, Hefle SL,  Bindslev-Jensen C, Atkins FM, Andre C, Bruijnzeel-Koomen C, Burks AW, Bush RK, Ebisawa M, Eigenmann PA, Host A, Hourihane JO, Isolauri E, Hill DJ, Knulst A, Lack G, Sampson HA, Moneret-Vautrin DA, Rance F, Vadas P, Yunginger JW, Zeiger RS, Salminen JW, Madsen C, Abbott P.  A consensus protocol for the determination of the threshold doses for allergenic foods: how much is too much?  Clin  Exp Allergy. 2004 May;34(5):689-95.

§  Tsai E, Yeung J, Gold M, Sussman G, Perelman B, Vadas P. Study of the allergenicity of plant protein hydrolysates. Food Allergy and Intolerance. Vol. 4, Issue 2:117-126. 2003.

§  Vadas P. Food allergens and anaphylaxis. Insert to the Canadian Journal of Dietetic Practice and Research. Vol. 64, No. 2, Summer 2003

§  Taylor S, Hefle SL, Bindslev-Jensen C, Bock SA, Burks AW Jr., Christie L, Hill DJ, Host A, Hourihane J O’B, Lack G, Metcalfe DD, Moneret-Vautrin DA, Vadas P, Rance F, Skrypec DJ, Trautman TA, Yman IM, Zeiger RS. Factors affecting the determination of threshold doses for allergenic foods: how much is too much? Report of an international conference sponsored by Food Allergy Research & Resource Program. JACI. 109:24-30. January 2002.

§  Vadas P. Celery Sticks Gone Wrong: An Unexpected Reaction. Case of the Month - The Canadian Journal of Diagnosis. November 2002.

§  Vadas P. Systemic cold urticaria. The Canadian Journal of Diagnosis. February 2001.

§  Vadas P. Allergy to insect venom. Chronicle of Skin and Allergy. March 2001.

§  Vadas P. Prevention of anaphylaxis in the office setting. Members Dialogue (College of Physicians and Surgeons of Ontario). March 2001.

§  Vadas P, Sussman G, Perelman B. Anaphylaxis to Cottonseed Protein. Cdn J Allergy Clin Imm 2000.

§  Vadas P, Gold M, Evans M. Managing Anaphylaxis: Q&A. The Medical Post 2000

§  Vadas P. You can’t judge a chocolate bar by its cover: get the facts behind the label. Anaphylaxis Network Newsletter. December 2000.

§  Vadas P, Gold M. Criteria for development of a priority allergen list: Application to sesame seed. Cdn J Allergy Clin Imm, 3:4:8-10, 1998.

§  Vadas P, Gold M, Graham C. Diagnosis and emergency management of anaphylaxis. Allergy Sept. 1998, pages 16 – 22.

§  Dyck ED, Vadas P. Anaphylaxis following the application of topical bacitracin. Eur. J. of Allergy & Clin. Imm. 52(8):870-871, 1997.

§  Mace S, Vadas P, Pruzanski W.  Anaphylactic shock induced by intraarticular injection of methylprednisolone  acetate.  J Rheumatol. 1997 Jun;24(6):1191-4.

§  Vadas P. Latex-rubber Hypersensitivity. Allergy 10(4):31-32, 1997.

§  Graham C, Vadas P. Systemic allergic reactions to corticosteroids. Practical Allergy and Immunology 10(5):182-185, 1995.

§  Vadas P, Sussman G. Anaphylaxis:Investigation and management at the Regional Anaphylaxis Clinic. Contemporary Allergies 4:4-8, 1994.

§  Vadas P, Sussman G. Allergy to peanuts and related foods. Contemporary Allergies 3:10-18, 1993

§  Vadas P, Sussman G. Idiopathic anaphylactic reactions: diagnosis and management. Practical Allergy Immunol. 6(3):95-98, 1991.

Non-Peer Reviewed Publications

§  Vadas P. Do all shellfish allergy patients require an epinephrine injection? The Canadian Journal of CME. April 2008.

§  Vadas P. Remind anaphylactic patients about proper management, up-to-date meds. The Medical Post. 2007 January 23.

§  Vadas P. Fish allergy. The Canadian Journal of CME. February 2007.

§  Vadas P. Be Aware, Be Prepared. Key Management Strategies. Clinical Focus on Anaphylaxis. Medical Post Supplement. February 2006.

§  Vadas P. Pregnancy and peanut avoidance. Is there evidence for peanut avoidance during pregnancy? If so, what is the risk of severe allergies developing in childhood?  The Canadian Journal of CME. April 2006.

§  Vadas P. Parental anaphylaxis. Is history of parental anaphylaxis to medication (e.g. penicillin) significant? What about other first-degree relatives? The Canadian Journal of CME. April 2006.

§  Vadas P. Immunizing children with egg allergies: What are the pros and cons of immunizing children with egg allergies for the flu? The Canadian Journal of CME. June 2006.

§  Alsowaidi S, Vadas P. Peanut allergy: An overview. Allergy & Asthma. A Canadian Review for Primary Care Physicians. Summer 2006.

§  Vadas P. Epinephrine and allergies. Other than peanut and penicillin allergies, which other allergies justify an epinephrine prescription? The Canadian Journal of CME. October 2005.

§  Vadas P. On the Table: Food Allergies. The Canadian Journal of Diagnosis. August 2003.

§  Vadas P. Latex-Rubber Hypersensitivity. Allergy, 10(4):31-32, 1997.